kgp Antibody (PACO53814)
- SKU:
- PACO53814
- Product Type:
- Antibody
- Reactivity:
- Bacteria
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | kgp Antibody (PACO53814) |
| Antibody SKU: | PACO53814 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Porphyromonas gingivalis |
| Immunogen: | Recombinant Porphyromonas gingivalis Lys-gingipain protein (229-594AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: kgp antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 56 kDa. Observed band size: 56 kDa. |
| Background: | Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. |
| Synonyms: | Lys-gingipain (EC 3.4.22.47) (Lysine-specific cysteine proteinase Kgp) [Cleaved into: Lys-gingipain catalytic subunit; 39 kDa adhesin; 15 kDa adhesin; 44 kDa adhesin], kgp |
| UniProt Protein Function: | Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | B2RLK2 |
| NCBI GenInfo Identifier: | 501433833 |
| NCBI Gene ID: | |
| NCBI Accession: | WP_012458488.1 |
| UniProt Secondary Accession: | B2RLK2 |
| UniProt Related Accession: | B2RLK2 |
| Molecular Weight: | |
| NCBI Full Name: | peptidase C25 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Lys-gingipain |
| UniProt Synonym Protein Names: | Lysine-specific cysteine proteinase Kgp |
| Protein Family: | Lys-gingipain |
| UniProt Gene Name: | kgp |
| UniProt Entry Name: |
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