KDM4A Monoclonal Antibody
- SKU:
- CAB22060
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
Description
| Product Name: | KDM4A Monoclonal Antibody |
| Product Code: | CAB22060 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52943 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:20000, IP 1:2000-1:20000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, NIH/3T3, Rat brain |
| Cellular Location: | Nucleus |
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 382-459 of human KDM4A (NP_055478.2). |
| Sequence: | EGDLK TSLAK HRIGT KRHRV CLEIP QEVSQ SELFP KEDLS SEQYE MTECP AALAP VRPTH SSVRQ VEDGL TFPDY SDS |
| Synonyms: | JMJD2, JHDM3A, JMJD2A, TDRD14A |
| Calculated MW: | 121kDa |
| Observed MW: | 150kDa |
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