[KD Validated] VDAC1 Polyclonal Antibody

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SKU:
CAB21730
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:[KD Validated] VDAC1 Polyclonal Antibody
Product Code:CAB21730
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:293T, Mouse heart, Rat kidney, Rat heart
Cellular Location:Cell membrane, Membrane raft, Mitochondrion outer membrane, Multi-pass membrane protein

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human VDAC1 (NP_003365.1).
Sequence:MAVPP TYADL GKSAR DVFTK GYGFG LIKLD LKTKS ENGLE FTSSG SANTE TTKVT GSLET KYRWT EYGLT FTEKW NTDNT LGTEI TVEDQ LARGL KLTFD SSFSP NTGKK NAKIK TGYKR EHINL GCDMD FDIAG PSIRG ALVLG YEGWL AGYQM NFETA KSRVT QSNFA VGYKT DEFQL HTNVN DGTEF GGSIY QKVNK KLETA VNLAW TAGNS NTRFG IAAKY QIDPD ACFSA KVNNS SLIGL GYTQT LKPGI KLTLS ALLDG KNVNA GGHKL GLGLE FQA
Synonyms:PORIN, VDAC-1
Calculated MW:31kDa
Observed MW:32kDa
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