Description
Product Name: | [KD Validated] TOLLIP Polyclonal Antibody |
Product Code: | CAB21551 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | 293T, SW620, Mouse testis, Mouse brain, Rat testis |
Cellular Location: | Cytoplasm |
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human TOLLIP (NP_061882.2). |
Sequence: | MATTV STQRG PVYIG ELPQD FLRIT PTQQQ RQVQL DAQAA QQLQY GGAVG TVGRL NITVV QAKLA KNYGM TRMDP YCRLR LGYAV YETPT AHNGA KNPRW NKVIH CTVPP GVDSF YLEIF DERAF SMDDR IAWTH ITIPE SLRQG KVEDK WYSLS GRQGD DKEGM INLVM SYALL PAAMV MPPQP VVLMP TVYQQ GVGYV PITGM PAVCS PGMVP VALPP AAVNA QPRCS EEDLK AIQDM FPNMD QEVIR SVLEA QRGNK DAAIN SLLQM GEEP |
Synonyms: | IL-1RAcPIP |
Calculated MW: | 30kDa |
Observed MW: | 30kDa |