Description
| Product Name: | [KD Validated] TOLLIP Monoclonal Antibody |
| Product Code: | CAB23780 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61374 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, SW260, Mouse testis, Rat testis |
| Cellular Location: | Cytoplasm |
This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant protein of human TOLLIP. |
| Sequence: | Email for sequence |
| Synonyms: | TOLLIP, IL-1RAcPIP, toll-interacting protein |
| Calculated MW: | 22kDa/30kDa |
| Observed MW: | 33kDa |