Description
| Product Name: | [KD Validated] Sharpin Monoclonal Antibody |
| Product Code: | CAB24809 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64384 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, PC-3, Rat thymus |
| Cellular Location: | Cytoplasm |
Enables polyubiquitin modification-dependent protein binding activity. Involved in protein linear polyubiquitination and regulation of signal transduction. Located in cytosol. Part of LUBAC complex.
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 1-126 of human SHARPIN(NP_112236.3). |
| Sequence: | MAPPA GGAAA AASDL GSAAV LLAVH AAVRP LGAGP DAEAQ LRRLQ LSADP ERPGR FRLEL LGAGP GAVNL EWPLE SVSYT IRGPT QHELQ PPPGG PGTLS LHFLN PQEAQ RWAVL VRGAT VEGQN G |
| Synonyms: | SIPL1 |
| Calculated MW: | 40kDa |
| Observed MW: | 43kDa |