Description
| Product Name: | [KD Validated] SFRP2 Polyclonal Antibody |
| Product Code: | CAB22017 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | extracellular space |
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SFRP2 (NP_003004.1). |
| Sequence: | MLQGP GSLLL LFLAS HCCLG SARGL FLFGQ PDFSY KRSNC KPIPA NLQLC HGIEY QNMRL PNLLG HETMK EVLEQ AGAWI PLVMK QCHPD TKKFL CSLFA |
| Synonyms: | FRP-2, SARP1, SDF-5 |
| Calculated MW: | 33kDa |
| Observed MW: | 33kDa |