Description
Product Name: | [KD Validated] RARG Polyclonal Antibody |
Product Code: | CAB21785 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, SK-BR-3 |
Cellular Location: | Nucleus |
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RARG (NP_000957.1). |
Sequence: | MATNK ERLFA AGALG PGSGY PGAGF PFAFP GALRG SPPFE MLSPS FRGLG QPDLP KEMAS LSVET QSTSS |
Synonyms: | RARC, NR1B3, RARgamma |
Calculated MW: | 50kDa |
Observed MW: | 48kDa |