[KD Validated] MT2A Polyclonal Antibody

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SKU:
CAB22103
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:[KD Validated] MT2A Polyclonal Antibody
Product Code:CAB22103
Reactivity:Human, Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:293T, U2OS, U-87MG, Mouse liver, Mouse testis, Mouse kidney
Cellular Location:cytoplasm, cytosol, nucleus

This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-61 of human MT2A (NP_005944.1).
Sequence:MDPNC SCAAG DSCTC AGSCK CKECK CTSCK KSCCS CCPVG CAKCA QGCIC KGASD KCSCC A
Synonyms:MT2, MT-2, MT-II
Calculated MW:6kDa
Observed MW:15kDa
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