Description
Product Name: | [KD Validated] ISG15 Polyclonal Antibody |
Product Code: | CAB21995 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa |
Cellular Location: | cytoplasm, cytosol, extracellular region, nucleoplasm, nucleus |
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_005092.1). |
Sequence: | MGWDL TVKML AGNEF QVSLS SSMSV SELKA QITQK IGVHA FQQRL AVHPS GVALQ DRVPL ASQGL GPGST VLLVV DKCDE PLSIL VRNNK GRSST YEVRL TQTVA HLKQQ VSGLE GVQDD LFWLT FEGKP LEDQL PLGEY GLKPL STVFM NLRLR GGGTE PGGRS |
Synonyms: | G1P2, IP17, UCRP, IFI15, IMD38, hUCRP |
Calculated MW: | 18kDa |
Observed MW: | 15kDa |