[KD Validated] Integrin alpha 5 (ITGA5/CD49e) Monoclonal Antibody

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SKU:
CAB22706
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:[KD Validated] Integrin alpha 5 (ITGA5/CD49e) Monoclonal Antibody
Product Code:CAB22706
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58291
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HeLa, A-549
Cellular Location:Membrane, Single-pass type I membrane protein

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Immunogen:Recombinant protein of human Integrin alpha 5 (ITGA5/CD49e).
Sequence:Email for sequence
Synonyms:FNRA, CD49e, VLA-5, VLA5A
Calculated MW:115kDa
Observed MW:150kDa
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