Description
| Product Name: | [KD Validated] FOSL1 Polyclonal Antibody |
| Product Code: | CAB21988 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | U-87MG |
| Cellular Location: | Nucleus |
| Customer Validation: | IF(Mus musculus) |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FOSL1 (NP_005429.1?). |
| Sequence: | MFRDF GEPGP SSGNG GGYGG PAQPP AAAQA AQQKF HLVPS INTMS GSQEL QWMVQ PHFLG PSSYP RPLTY PQYSP PQPRP GVIRA LGPPP GVRRR PCEQI |
| Synonyms: | FRA, FRA1, fra-1 |
| Calculated MW: | 29kDa |
| Observed MW: | 40kDa |