Description
Product Name: | [KD Validated] FOSL1 Polyclonal Antibody |
Product Code: | CAB21988 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | U-87MG |
Cellular Location: | Nucleus |
Customer Validation: | IF(Mus musculus) |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FOSL1 (NP_005429.1?). |
Sequence: | MFRDF GEPGP SSGNG GGYGG PAQPP AAAQA AQQKF HLVPS INTMS GSQEL QWMVQ PHFLG PSSYP RPLTY PQYSP PQPRP GVIRA LGPPP GVRRR PCEQI |
Synonyms: | FRA, FRA1, fra-1 |
Calculated MW: | 29kDa |
Observed MW: | 40kDa |