Description
Product Name: | [KD Validated] BUB1 Monoclonal Antibody |
Product Code: | CAB23198 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59688 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HEL, 293T |
Cellular Location: | Chromosome, Nucleus, centromere, kinetochore |
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Immunogen: | Recombinant protein of human BUB1. |
Sequence: | Email for sequence |
Synonyms: | BUB1A, BUB1L, hBUB1, MCPH30 |
Calculated MW: | 115KDa/120KDa/122KDa |
Observed MW: | 122kDa |