Description
| Product Name: | [KD Validated] beta 2 Microglobulin Monoclonal Antibody |
| Product Code: | CAB23430 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60950 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, FC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, FC 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | THP-1, HeLa, U-937 |
| Cellular Location: | Secreted, Cell surface |
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-119 of human β2 Microglobulin(NP_004039.1). |
| Sequence: | IQRTP KIQVY SRHPA ENGKS NFLNC YVSGF HPSDI EVDLL KNGER IEKVE HSDLS FSKDW SFYLL YYTEF TPTEK DEYAC RVNHV TLSQP KIVKW DRDM |
| Synonyms: | B2M, IMD43, beta-2-microglobulin |
| Calculated MW: | 13kDa |
| Observed MW: | 12kDa |