[KD Validated] Aurora B Monoclonal Antibody

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SKU:
CAB21918
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF

Description

Product Name:[KD Validated] Aurora B Monoclonal Antibody
Product Code:CAB21918
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC50892
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:500-1:1000, IF/ICC 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Jurkat, NIH/3T3, C6, 293T
Cellular Location:Chromosome, Cytoplasm, Midbody, Nucleus, centromere, cytoskeleton, spindle

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aurora B (NP_004208.2).
Sequence:MAQKE NSYPW PYGRQ TAPSG LSTLP QRVLR KEPVT PSALV LMSRS NVQPT AAPGQ KVMEN SSGTP DILTR HFTID DFEIG RPLGK GKFGN VYLAR EKKSH
Synonyms:AIK2, AIM1, ARK2, AurB, IPL1, STK5, AIM-1, ARK-2, STK-1, STK12, PPP1R48, aurkb-sv1, aurkb-sv2
Calculated MW:39kDa
Observed MW:39kDa
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