Description
| Product Name: | [KD Validated] Ajuba Monoclonal Antibody |
| Product Code: | CAB22039 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54979 |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, IP, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:20000, IP 1:10000-1:90000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, Rat lung |
| Cellular Location: | adherens junction, cell-cell junction, cytosol, Golgi apparatus, microtubule organizing center, nucleoplasm, nucleus, P-body, plasma membrane |
Enables alpha-catenin binding activity and transcription corepressor activity. Involved in several processes, including negative regulation of hippo signaling; positive regulation of gene silencing by miRNA; and regulation of cellular response to hypoxia. Acts upstream of or within gene silencing by miRNA and positive regulation of protein-containing complex assembly. Located in several cellular components, including Golgi apparatus; P-body; and nucleoplasm.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-290 of human Ajuba (NP_116265.1). |
| Sequence: | PSAYP ELHAA LDRLY AQRPA GFGCQ ESRHS YPPAL GSPGA LAGAG VGAAG PLERR GAQPG RHSVT GYGDC AVGAR YQDEL TALLR LTVGT |
| Synonyms: | JUB |
| Calculated MW: | 57kDa |
| Observed MW: | 55kDa |