[KD Validated] ABCG2 Polyclonal Antibody
![[KD Validated] ABCG2 Polyclonal Antibody](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/82962/87749/A23066_1__84767__26086.1706547545.jpg?c=1 "[KD Validated] ABCG2 Polyclonal Antibody")
- SKU:
- CAB23066
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
![[KD Validated] ABCG2 Polyclonal Antibody](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/82962/87749/A23066_1__84767__26086.1706547545.jpg?c=1&imbypass=on "[KD Validated] ABCG2 Polyclonal Antibody")
Description
| Product Name: | [KD Validated] ABCG2 Polyclonal Antibody |
| Product Code: | CAB23066 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, A-549, MCF7 |
| Cellular Location: | Cell membrane, Mitochondrion membrane, Multi-pass membrane protein |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant protein of human ABCG2. |
| Sequence: | SGLSG DVLIN GAPRP ANFKC NSGYV VQDDV VMGTL TVREN LQFSA ALRLA TTMTN HEKNE RINRV IQELG LDKVA DSKVG TQFIR GVSGG ERKRT SIGME L |
| Synonyms: | MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, MXR-1, CDw338, CDw388, UAQTL1, EST157481 |
| Calculated MW: | 72kDa |
| Observed MW: | 65-80kDa |
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