Description
| Product Name: | [KD Validated] ABCA6 Polyclonal Antibody |
| Product Code: | CAB21243 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, RAW264.7, Mouse liver, Rat liver |
| Cellular Location: | Membrane, Multi-pass membrane protein |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1518-1617 of human ABCA6 (NP_525023.2). |
| Sequence: | SQVTL VHTEI LKLFP QAAGQ ERYSS LLTYK LPVAD VYPLS QTFHK LEAVK HNFNL EEYSL SQCTL EKVFL ELSKE QEVGN FDEEI DTTMR WKLLP HSDEP |
| Synonyms: | EST155051 |
| Calculated MW: | 184kDa |
| Observed MW: | 180kDa |