KCNK13 Antibody (PACO16580)
- SKU:
- PACO16580
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KCNK13 Antibody (PACO16580) |
| Antibody SKU: | PACO16580 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human KCNK13 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse lung tissue, Primary antibody: PACO16580(KCNK13 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16580(KCNK13 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid, and inhibited by the anesthetic halothane. |
| Synonyms: | potassium channel, subfamily K, member 13 |
| UniProt Protein Function: | KCNK13: Potassium channel displaying weak inward rectification in symmetrical K(+) solution. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 14q32.11Cellular Component: integral to membrane; plasma membraneMolecular Function: potassium channel activity; voltage-gated ion channel activityBiological Process: synaptic transmission |
| UniProt Protein Details: | |
| NCBI Summary: | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9HB14 |
| NCBI GenInfo Identifier: | 16306555 |
| NCBI Gene ID: | 56659 |
| NCBI Accession: | NP_071337.2 |
| UniProt Secondary Accession: | Q9HB14,Q96E79 |
| UniProt Related Accession: | Q9HB14 |
| Molecular Weight: | 45,391 Da |
| NCBI Full Name: | potassium channel subfamily K member 13 |
| NCBI Synonym Full Names: | potassium channel, subfamily K, member 13 |
| NCBI Official Symbol: | KCNK13 |
| NCBI Official Synonym Symbols: | THIK1; THIK-1; K2p13.1 |
| NCBI Protein Information: | potassium channel subfamily K member 13; K2P13.1 potassium channel; tandem pore domain potassium channel THIK-1; tandem pore domain halothane-inhibited potassium channel 1 |
| UniProt Protein Name: | Potassium channel subfamily K member 13 |
| UniProt Synonym Protein Names: | Tandem pore domain halothane-inhibited potassium channel 1 |
| Protein Family: | Potassium channel subfamily |
| UniProt Gene Name: | KCNK13 |
| UniProt Entry Name: | KCNKD_HUMAN |
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