KCNG3 Antibody (PACO19882)
- SKU:
- PACO19882
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KCNG3 Antibody (PACO19882) |
| Antibody SKU: | PACO19882 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:10-1:50 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human KCNG3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19882(KCNG3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO19882(KCNG3 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19882(KCNG3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a γ subunit functioning as a modulatory molecule. |
| Synonyms: | potassium voltage-gated channel, subfamily G, member 3 |
| UniProt Protein Function: | KCNG3: Potassium channel subunit. Modulates channel activity. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 2p21Cellular Component: endoplasmic reticulum; plasma membrane; voltage-gated potassium channel complexMolecular Function: delayed rectifier potassium channel activity; protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TAE7 |
| NCBI GenInfo Identifier: | 24418472 |
| NCBI Gene ID: | 170850 |
| NCBI Accession: | Q8TAE7.1 |
| UniProt Secondary Accession: | Q8TAE7,Q53SC1 |
| UniProt Related Accession: | Q8TAE7 |
| Molecular Weight: | 48,534 Da |
| NCBI Full Name: | Potassium voltage-gated channel subfamily G member 3 |
| NCBI Synonym Full Names: | potassium voltage-gated channel modifier subfamily G member 3 |
| NCBI Official Symbol: | KCNG3 |
| NCBI Official Synonym Symbols: | KV6.3; KV10.1 |
| NCBI Protein Information: | potassium voltage-gated channel subfamily G member 3 |
| UniProt Protein Name: | Potassium voltage-gated channel subfamily G member 3 |
| UniProt Synonym Protein Names: | Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3 |
| Protein Family: | Potassium voltage-gated channel subfamily |
| UniProt Gene Name: | KCNG3 |
| UniProt Entry Name: | KCNG3_HUMAN |
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