KCMF1 Antibody (PACO58524)
- SKU:
- PACO58524
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KCMF1 Antibody (PACO58524) |
| Antibody SKU: | PACO58524 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:500-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human E3 ubiquitin-protein ligase KCMF1 protein (98-226AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58524 diluted at 1:500 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO58524 diluted at 1:500 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination. |
| Synonyms: | E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (RING-type E3 ubiquitin transferase KCMF1) (ZZ-type zinc finger-containing protein 1), KCMF1, FIGC ZZZ1 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9P0J7 |
| NCBI GenInfo Identifier: | 150456454 |
| NCBI Gene ID: | 56888 |
| NCBI Accession: | NP_064507.3 |
| UniProt Secondary Accession: | Q9P0J7,Q4ZG04, Q53SC7, Q9BWK2, Q9H8P5, Q9UFE8 |
| UniProt Related Accession: | Q9P0J7 |
| Molecular Weight: | 41,945 Da |
| NCBI Full Name: | Homo sapiens potassium channel modulatory factor 1 (KCMF1), mRNA |
| NCBI Synonym Full Names: | potassium channel modulatory factor 1 |
| NCBI Official Symbol: | KCMF1 |
| NCBI Official Synonym Symbols: | FIGC; PCMF; ZZZ1; DEBT91 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase KCMF1; FGF-induced in gastric cancer; FGF-induced ubiquitin-protein ligase in gastric cancers; ZZ-type zinc finger-containing protein 1; differentially expressed in branching tubulogenesis 91; zinc finger, ZZ domain containing |
| UniProt Protein Name: | E3 ubiquitin-protein ligase KCMF1 |
| UniProt Synonym Protein Names: | FGF-induced in gastric cancer; Potassium channel modulatory factor; PCMF; ZZ-type zinc finger-containing protein 1 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | KCMF1 |
| UniProt Entry Name: | KCMF1_HUMAN |
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