Description
Antibody Name: | KATNAL2 Antibody (PACO37634) |
Antibody SKU: | PACO37634 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Katanin p60 ATPase-containing subunit A-like 2 protein (18-307AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: KATNAL2 antibody at 1µg/ml + U251 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62, 53 kDa. Observed band size: 62 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human breast cancer using PACO37634 at dilution of 1:100. |
Background: | Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. |
Synonyms: | Katanin p60 ATPase-containing subunit A-like 2 (Katanin p60 subunit A-like 2) (EC 3.6.4.3) (p60 katanin-like 2), KATNAL2 |
UniProt Protein Function: | KATNAL2: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.6.4.3; HydrolaseChromosomal Location of Human Ortholog: 18q21.1Cellular Component: microtubule; cytoplasm; nucleusMolecular Function: microtubule binding; microtubule-severing ATPase activity; ATP bindingBiological Process: metabolic process; microtubule severing; cytoplasmic microtubule organization and biogenesis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8IYT4 |
NCBI GenInfo Identifier: | 226371754 |
NCBI Gene ID: | 83473 |
NCBI Accession: | NP_112593.2 |
UniProt Secondary Accession: | Q8IYT4 |
UniProt Related Accession: | Q8IYT4 |
Molecular Weight: | |
NCBI Full Name: | katanin p60 ATPase-containing subunit A-like 2 |
NCBI Synonym Full Names: | katanin p60 subunit A-like 2 |
NCBI Official Symbol: | KATNAL2 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | katanin p60 ATPase-containing subunit A-like 2; KATNAL2; p60 katanin-like 2 |
UniProt Protein Name: | Katanin p60 ATPase-containing subunit A-like 2 |
UniProt Synonym Protein Names: | p60 katanin-like 2 |
Protein Family: | Katanin p60 ATPase-containing |
UniProt Gene Name: | KATNAL2 |
UniProt Entry Name: | KATL2_HUMAN |