KAT2B/PCAF Monoclonal Antibody (CAB22719)
- SKU:
- CAB22719
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
Product Name: | KAT2B/PCAF Monoclonal Antibody |
Product Code: | CAB22719 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC55963 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:2000-1:8000, IHC-P 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HepG2 |
Cellular Location: | Nucleus |
CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-450 of human KAT2B/PCAF (NP_003875.3). |
Sequence: | QNSPI WDQDF LSASS RTSQL GIQTV INPPP VAGTI SYNST SSSLE QPNAG SSSPA CKASS GLEAN PGEKR KMTDS HVLEE AKKPR VMGDI P |
Synonyms: | CAF, PCAF, P/CAF |
Calculated MW: | 93kDa |
Observed MW: | 101kDa |