KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)
![KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58324/63506/kat2a-monoclonal-antibody-pat3g13at-cpab0097__72265__24986.1706534971.jpg?c=1 "KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)")
- SKU:
- CPAB0097
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT3G13AT
- Applications:
- WB
- Applications:
- IF
- Applications:
- ELISA
![KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58324/63506/kat2a-monoclonal-antibody-pat3g13at-cpab0097__72265__24986.1706534971.jpg?c=1&imbypass=on "KAT2A Monoclonal Antibody [PAT3G13AT] (CPAB0097)")
Description
system_update_alt Datasheet
| Product Name: | KAT2A Antibody |
| Product Sku: | CPAB0097 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human KAT2A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KAT2A amino acids 411-837 purified from Ecoli. |
| Clone: | PAT3G13AT. |
| Reactivity: | Human |
| Applications: | Western Blot, Immunofluorescence, ELISA |
| Purification Method: | KAT2A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | KAT2A (GCN5L2 or GCN5) is a histone acetyltransferase (HAT), which functions mainly as a transcriptional activator. GCN5L2 may be one of the enzymes involved in acetylation in vivo. GCN5 is expressed primarily in the embryo and newborn and is crucial for normal embryonic development. Hence, KAT2A appears to be significant for differentiation of embryonic-derived preadipocytes. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner. Loss of GCN5L2 leads to a high occurrence of apoptosis in the KAT2A mutants, which begins before the onset of morphological abnormality. |
| Synonyms: | Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5, PCAF-b, MGC102791. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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