JunD (Phospho-Ser255) Transcription Factor Activity Assay
- SKU:
- TFAB00011
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- JunD (Phospho-Ser255)
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
Description
| Product Name: | JunD (Phospho-Ser255) Transcription Factor Activity Assay |
| Product Code: | TFAB00011 |
| Target: | JunD (Phospho-Ser255) |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie JunD (Phospho-Ser255) transcription factor activity assay allows for the detection and qualitative analysis of JunD (Phospho-Ser255) active transcription factors in eukaryotic nuclear or cell lysates.
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily. |
| UniProt Protein Details: | Protein type:Transcription factor; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: chromatin; nuclear chromatin; nucleus; transcription factor complex Molecular Function:enzyme binding; ligand-dependent nuclear receptor binding; protein binding; transcription coactivator activity; transcription factor binding Biological Process: aging; cellular response to hormone stimulus; circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; osteoblast development; positive regulation of cell differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to light stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to peptide hormone stimulus; response to radiation; transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013] |
| UniProt Code: | P17535 |
| NCBI GenInfo Identifier: | 229462969 |
| NCBI Gene ID: | 3727 |
| NCBI Accession: | P17535.3 |
| UniProt Secondary Accession: | P17535,Q53EK9, |
| UniProt Related Accession: | P17535 |
| Molecular Weight: | 35,174 Da |
| NCBI Full Name: | Transcription factor jun-D |
| NCBI Synonym Full Names: | jun D proto-oncogene |
| NCBI Official Symbol: | JUND |
| NCBI Official Synonym Symbols: | AP-1 |
| NCBI Protein Information: | transcription factor jun-D |
| UniProt Protein Name: | Transcription factor jun-D |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | JUND |
| UniProt Entry Name: | JUND_HUMAN |
