Description
| Product Name: | JunD Monoclonal Antibody |
| Product Code: | CAB22466 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56604 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, Jurkat |
| Cellular Location: | nucleoplasm, nucleus |
The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216).
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human JunD (NP_005345.3). |
| Sequence: | YAGGA GGAGG AATVA FAAEP VPFPP PPPPG ALGPP RLAAL KDEPQ TVPDV PSFGE SPPLS PIDMD TQERI KAERK RLRNR IAASK CRKRK LERIS RLEEK V |
| Synonyms: | AP-1 |
| Calculated MW: | 35kDa |
| Observed MW: | 38kDa/42kDa |