Description
Product Name: | JunB (Phospho-Ser259) Transcription Factor Activity Assay |
Product Code: | TFAB00010 |
Target: | JunB (Phospho-Ser259) |
Reactivity: | Human, Mouse |
Sample Types: | Nuclear or cell lysates |
The Assay Genie JunB (Phospho-Ser259) transcription factor activity assay allows for the detection and qualitative analysis of JunB (Phospho-Ser259) active transcription factors in eukaryotic nuclear or cell lysates.
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
Assay Time: | 4.5 hours |
Detection Method: | Colorimetric 450 nm |
Size: | 12 x 8-Well Microstrips |
Storage: | 4°C for 6 months |
UniProt Protein Function: | JunB: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'. Binds DNA as an homodimer or as an heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains). By growth factors. Belongs to the bZIP family. Jun subfamily. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Transcription factor; Oncoprotein Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: chromatin; nuclear chromatin; nucleoplasm; transcription factor complex Molecular Function:DNA binding; protein binding; transcription coactivator activity; transcription corepressor activity; transcription factor binding Biological Process: cellular response to hormone stimulus; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to lipopolysaccharide; response to mechanical stimulus; response to radiation |
UniProt Code: | P17275 |
NCBI GenInfo Identifier: | 135304 |
NCBI Gene ID: | 3726 |
NCBI Accession: | P17275.1 |
UniProt Secondary Accession: | P17275,Q96GH3, |
UniProt Related Accession: | P17275 |
Molecular Weight: | 35,879 Da |
NCBI Full Name: | Transcription factor jun-B |
NCBI Synonym Full Names: | JunB proto-oncogene, AP-1 transcription factor subunit |
NCBI Official Symbol: | JUNB |
NCBI Official Synonym Symbols: | AP-1 |
NCBI Protein Information: | transcription factor jun-B |
UniProt Protein Name: | Transcription factor jun-B |
Protein Family: | Transcription factor |
UniProt Gene Name: | JUNB |
UniProt Entry Name: | JUNB_HUMAN |