Description
| Product Name: | ITPR3 Monoclonal Antibody |
| Product Code: | CAB23202 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59549 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:6000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | SW620, HEL(Negative control) |
| Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
This gene encodes a receptor for inositol 1, 4, 5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1, 4, 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
| Immunogen: | Recombinant protein of human ITPR3. |
| Sequence: | Email for sequence |
| Synonyms: | IP3R, CMT1J, IP3R3 |
| Calculated MW: | 304kDa |
| Observed MW: | 300kDa |