ITIH5 Antibody (PACO37238)
- SKU:
- PACO37238
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ITIH5 Antibody (PACO37238) |
| Antibody SKU: | PACO37238 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H5 protein (35-161AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO37238 at dilution of 1:100. |
| Background: | May act as a tumor suppressor. |
| Synonyms: | Inter-alpha-trypsin inhibitor heavy chain H5 (ITI heavy chain H5) (ITI-HC5) (Inter-alpha-inhibitor heavy chain 5), ITIH5, KIAA1953 |
| UniProt Protein Function: | ITIH5: May act as a tumor suppressor. Belongs to the ITIH family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 10p14 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q86UX2 |
| NCBI GenInfo Identifier: | 187609608 |
| NCBI Gene ID: | 80760 |
| NCBI Accession: | Q86UX2.2 |
| UniProt Secondary Accession: | Q86UX2,Q5T664, Q5T665, Q5T666, Q6AI60, Q6UXB7, Q8TF48 Q8WYV2, Q96K70 |
| UniProt Related Accession: | Q86UX2 |
| Molecular Weight: | 27,191 Da |
| NCBI Full Name: | Inter-alpha-trypsin inhibitor heavy chain H5 |
| NCBI Synonym Full Names: | inter-alpha-trypsin inhibitor heavy chain family member 5 |
| NCBI Official Symbol: | ITIH5 |
| NCBI Official Synonym Symbols: | ITI-HC5; PP14776 |
| NCBI Protein Information: | inter-alpha-trypsin inhibitor heavy chain H5 |
| UniProt Protein Name: | Inter-alpha-trypsin inhibitor heavy chain H5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Inter-alpha-trypsin inhibitor |
| UniProt Gene Name: | ITIH5 |
| UniProt Entry Name: | ITIH5_HUMAN |
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