Description
| Antibody Name: | ISX Antibody (PACO27669) |
| Antibody SKU: | PACO27669 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Intestine-specific homeobox protein (1-245AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO27669 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human glioma using PACO27669 at dilution of 1:100. |
| Background: | Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine (By similarity). |
| Synonyms: | Intestine-specific homeobox (RAX-like homeobox), ISX, RAXLX |
| UniProt Protein Function: | ISX: Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCMO1 expression in the intestine.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 22q12.3Cellular Component: nucleusMolecular Function: sequence-specific DNA bindingBiological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the RAXLX homeobox gene family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q2M1V0 |
| NCBI GenInfo Identifier: | 57232759 |
| NCBI Gene ID: | 91464 |
| NCBI Accession: | NP_001008494.1 |
| UniProt Secondary Accession: | Q2M1V0,Q68DJ5 |
| UniProt Related Accession: | Q2M1V0 |
| Molecular Weight: | 27,011 Da |
| NCBI Full Name: | intestine-specific homeobox |
| NCBI Synonym Full Names: | intestine-specific homeobox |
| NCBI Official Symbol: | ISX |
| NCBI Official Synonym Symbols: | Pix-1; RAXLX |
| NCBI Protein Information: | intestine-specific homeobox; RAX-like homeobox; pancreas-intestine homeodomain transcription factor |
| UniProt Protein Name: | Intestine-specific homeobox |
| UniProt Synonym Protein Names: | RAX-like homeobox |
| Protein Family: | Intestine-specific homeobox |
| UniProt Gene Name: | ISX |
| UniProt Entry Name: | ISX_HUMAN |

