Description
Antibody Name: | ISX Antibody (PACO27669) |
Antibody SKU: | PACO27669 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Intestine-specific homeobox protein (1-245AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO27669 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human glioma using PACO27669 at dilution of 1:100. |
Background: | Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine (By similarity). |
Synonyms: | Intestine-specific homeobox (RAX-like homeobox), ISX, RAXLX |
UniProt Protein Function: | ISX: Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCMO1 expression in the intestine.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 22q12.3Cellular Component: nucleusMolecular Function: sequence-specific DNA bindingBiological Process: regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent |
UniProt Protein Details: | |
NCBI Summary: | Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the RAXLX homeobox gene family. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q2M1V0 |
NCBI GenInfo Identifier: | 57232759 |
NCBI Gene ID: | 91464 |
NCBI Accession: | NP_001008494.1 |
UniProt Secondary Accession: | Q2M1V0,Q68DJ5 |
UniProt Related Accession: | Q2M1V0 |
Molecular Weight: | 27,011 Da |
NCBI Full Name: | intestine-specific homeobox |
NCBI Synonym Full Names: | intestine-specific homeobox |
NCBI Official Symbol: | ISX |
NCBI Official Synonym Symbols: | Pix-1; RAXLX |
NCBI Protein Information: | intestine-specific homeobox; RAX-like homeobox; pancreas-intestine homeodomain transcription factor |
UniProt Protein Name: | Intestine-specific homeobox |
UniProt Synonym Protein Names: | RAX-like homeobox |
Protein Family: | Intestine-specific homeobox |
UniProt Gene Name: | ISX |
UniProt Entry Name: | ISX_HUMAN |