ISCA2 Antibody (PACO37290)
- SKU:
- PACO37290
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ISCA2 Antibody (PACO37290) |
| Antibody SKU: | PACO37290 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Iron-sulfur cluster assembly 2 homolog, mitochondrial protein (9-154AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: ISCA2 antibody at 0.4µg/ml + HL60 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 17, 7 kDa. Observed band size: 17 kDa. |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO37290 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37290 at dilution of 1:100. |
| Background: | Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. |
| Synonyms: | Iron-sulfur cluster assembly 2 homolog, mitochondrial (HESB-like domain-containing protein 1), ISCA2, HBLD1 |
| UniProt Protein Function: | ISCA2: Involved in the assembly of mitochondrial iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family.Chromosomal Location of Human Ortholog: 14q24.3Cellular Component: mitochondrial matrixMolecular Function: 2 iron, 2 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; ferrous iron binding; protein binding; structural molecule activityBiological Process: iron-sulfur cluster assembly; sulfur metabolic processDisease: Multiple Mitochondrial Dysfunctions Syndrome 4 |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q86U28 |
| NCBI GenInfo Identifier: | 432134254 |
| NCBI Gene ID: | 122961 |
| NCBI Accession: | NP_001258936.1 |
| UniProt Secondary Accession: | Q86U28,Q8IYZ0, Q96BB2, A6NFF1, A8K3W3, G3V291 |
| UniProt Related Accession: | Q86U28 |
| Molecular Weight: | 6,211 Da |
| NCBI Full Name: | iron-sulfur cluster assembly 2 homolog, mitochondrial isoform 2 |
| NCBI Synonym Full Names: | iron-sulfur cluster assembly 2 |
| NCBI Official Symbol: | ISCA2 |
| NCBI Official Synonym Symbols: | ISA2; HBLD1; MMDS4; c14_5557 |
| NCBI Protein Information: | iron-sulfur cluster assembly 2 homolog, mitochondrial |
| UniProt Protein Name: | Iron-sulfur cluster assembly 2 homolog, mitochondrial |
| UniProt Synonym Protein Names: | HESB-like domain-containing protein 1 |
| Protein Family: | Iron-sulfur cluster assembly |
| UniProt Gene Name: | ISCA2 |
| UniProt Entry Name: | ISCA2_HUMAN |
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