Description
| Antibody Name: | IRX1 Antibody (PACO05356) |
| Antibody SKU: | PACO05356 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from the Internal region of human IRX1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | IRX1; IRXA1; Iroquois-class homeodomain protein IRX-1; Homeodomain protein IRXA1; Iroquois homeobox protein 1 |
| UniProt Protein Function: | IRX1: a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011] |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 5p15.3 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding Biological Process: regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011] |
| UniProt Code: | P78414 |
| NCBI GenInfo Identifier: | 51479177 |
| NCBI Gene ID: | 79192 |
| NCBI Accession: | NP_077313 |
| UniProt Related Accession: | P78414 |
| Molecular Weight: | 49kDa |
| NCBI Full Name: | iroquois-class homeodomain protein IRX-1 |
| NCBI Synonym Full Names: | iroquois homeobox 1 |
| NCBI Official Symbol: | IRX1 |
| NCBI Official Synonym Symbols: | IRX-5; IRXA1 |
| NCBI Protein Information: | iroquois-class homeodomain protein IRX-1 |
| UniProt Protein Name: | Iroquois-class homeodomain protein IRX-1 |
| UniProt Synonym Protein Names: | Homeodomain protein IRXA1; Iroquois homeobox protein 1 |
| Protein Family: | Iroquois-class homeodomain protein |
| UniProt Gene Name: | IRX1 |
| UniProt Entry Name: | IRX1_HUMAN |