IRGM Polyclonal Antibody (CAB10968)
- SKU:
- CAB10968
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IRGM Polyclonal Antibody |
| Product Code: | CAB10968 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3. |
| Positive Samples: | Mouse kidney, Mouse brain, Rat lung |
| Cellular Location: | Cell membrane, Cell projection, Cytoplasmic vesicle, Golgi apparatus membrane, autophagosome membrane, phagocytic cup, phagosome membrane |
| Customer Validation: | WB(Mus musculus) |
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | A synthetic peptide of human IRGM |
| Sequence: | Email for sequence |
| Synonyms: | IFI1, IBD19, IRGM1, LRG47, LRG-47 |
| Calculated MW: | 20kDa |
| Observed MW: | 34kDa |
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