IRGM Polyclonal Antibody (CAB10968)

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SKU:
CAB10968

Description

Product Name:IRGM Polyclonal Antibody
Product Code:CAB10968
Reactivity:Human, Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at 4°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, pH7.3.
Positive Samples:Mouse kidney, Mouse brain, Rat lung
Cellular Location:Cell membrane, Cell projection, Cytoplasmic vesicle, Golgi apparatus membrane, autophagosome membrane, phagocytic cup, phagosome membrane
Customer Validation:WB(Mus musculus)

This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen:A synthetic peptide of human IRGM
Sequence:Email for sequence
Synonyms:IFI1, IBD19, IRGM1, LRG47, LRG-47
Calculated MW:20kDa
Observed MW:34kDa
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Additional Information

Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
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