Description
Antibody Name: | Irf5 Antibody (PACO27661) |
Antibody SKU: | PACO27661 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Mouse |
Immunogen: | Recombinant Mouse Interferon regulatory factor 5 protein (1-497AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling. |
Synonyms: | Interferon regulatory factor 5 (IRF-5), Irf5 |
UniProt Protein Function: | IRF5: Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling. Homodimer, when phosphorylated. Belongs to the IRF family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Cellular Component: cytoplasm; nucleus Molecular Function:DNA binding; protein binding; transcription factor activity Biological Process: cytokine and chemokine mediated signaling pathway; defense response to virus; immune system process; innate immune response; positive regulation of apoptosis; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; response to muramyl dipeptide; response to peptidoglycan; transcription, DNA-dependent |
UniProt Code: | P56477 |
NCBI GenInfo Identifier: | 356991180 |
NCBI Gene ID: | 27056 |
NCBI Accession: | NP_001239311.1 |
UniProt Related Accession: | P56477 |
Molecular Weight: | 72 kDa |
NCBI Full Name: | interferon regulatory factor 5 isoform 1 |
NCBI Synonym Full Names: | interferon regulatory factor 5 |
NCBI Official Symbol: | Irf5 |
NCBI Official Synonym Symbols: | mirf5; AW491843 |
NCBI Protein Information: | interferon regulatory factor 5 |
UniProt Protein Name: | Interferon regulatory factor 5 |
Protein Family: | Interferon regulatory factor |
UniProt Gene Name: | Irf5 |
UniProt Entry Name: | IRF5_MOUSE |