IP3R Polyclonal Antibody
- SKU:
- CAB21471
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | IP3R Polyclonal Antibody |
| Product Code: | CAB21471 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Customer Validation: | Co-IP(Rattus norvegicus) |
This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1812-1911 of human IP3R (NP_001365381). |
| Sequence: | ASNLV IDLIM NASSD RVFHE SILLA IALLE GGNTT IQHSF FCRLT EDKKS EKFFK VFYDR MKVAQ QEIKA TVTVN TSDLG NKKKD DEVDR DAPSR KKAKE |
| Synonyms: | ACV, CLA4, IP3R, IP3R1, SCA15, SCA16, SCA29, INSP3R1, PPP1R94 |
| Calculated MW: | 314kDa |
| Observed MW: | Refer to figures |
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