Description
Product Name: | IP3R Monoclonal Antibody |
Product Code: | CAB23760 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC61062 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | SH-SY5Y |
Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
This gene encodes an intracellular receptor for inositol 1, 4, 5-trisphosphate. Upon stimulation by inositol 1, 4, 5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Immunogen: | A synthesized peptide derived from human IP3R. |
Sequence: | Email for sequence |
Synonyms: | ITPR1, ACV, CLA4, INSP3R1, IP3R, IP3R1, PPP1R94, SCA15, SCA16, SCA29, inositol 1, 4, 5-trisphosphate receptor type 1 |
Calculated MW: | 306-313kDa |
Observed MW: | 310kDa |