INTU Antibody (PACO60436)
- SKU:
- PACO60436
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | INTU Antibody (PACO60436) |
| Antibody SKU: | PACO60436 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein inturned protein (6-139AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO60436 diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of Hela cells with PACO60436 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | IHC image of PACO60436 diluted at 1:300 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. |
| Synonyms: | Protein inturned (Inturned planar cell polarity effector homolog) (PDZ domain-containing protein 6), INTU, KIAA1284 PDZD6 PDZK6 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9ULD6 |
| NCBI GenInfo Identifier: | 44888833 |
| NCBI Gene ID: | 27152 |
| NCBI Accession: | NP_056508 |
| UniProt Secondary Accession: | Q9ULD6 |
| UniProt Related Accession: | Q9ULD6 |
| Molecular Weight: | 104kDa |
| NCBI Full Name: | protein inturned |
| NCBI Synonym Full Names: | inturned planar cell polarity protein |
| NCBI Official Symbol: | INTU |
| NCBI Official Synonym Symbols: | INT; OFD17; PDZD6; PDZK6; SRTD20; CPLANE4 |
| NCBI Protein Information: | protein inturned |
| UniProt Protein Name: | Protein inturned |
| UniProt Synonym Protein Names: | Inturned planar cell polarity effector homolog; PDZ domain-containing protein 6 |
| Protein Family: | |
| UniProt Gene Name: | INTU |
| UniProt Entry Name: | INTU_HUMAN |
Related Products
Human TP53 antibody(p53 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
SPEF2 Antibody
Overview Product Name:SPEF2 AntibodyProduct Code:PACO64977Size:50µLTarget Names:SPEF2Species Reactivity:HumanHos
ompF Antibody
Overview Product Name:ompF AntibodyProduct Code:PACO64865Size:50µLTarget Names:ompFSpecies Reactivity:Escherichia coli
Hmgb1 Antibody
Overview Product Name:Hmgb1 AntibodyProduct Code:PACO64769Size:50µLTarget Names:Hmgb1Species Reactivity:RatHost
RIMS4 Antibody
Overview Product Name:RIMS4 AntibodyProduct Code:PACO64925Size:50µLTarget Names:RIMS4Species Reactivity:HumanHos