Description
| Antibody Name: | INTS12 Antibody (PACO09971) |
| Antibody SKU: | PACO09971 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human INTS12 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | integrator complex subunit 12;INTS12;INT12;PHF22;SBBI22 ; |
| UniProt Protein Function: | PHF22: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.Protein type: RNA-bindingChromosomal Location of Human Ortholog: 4q24Cellular Component: integrator complexMolecular Function: protein binding; zinc ion bindingBiological Process: snRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96CB8 |
| NCBI GenInfo Identifier: | 73621394 |
| NCBI Gene ID: | 57117 |
| NCBI Accession: | Q96CB8.1 |
| UniProt Secondary Accession: | Q96CB8,Q3B6Z3, Q9HD71, B2RC48 |
| UniProt Related Accession: | Q96CB8 |
| Molecular Weight: | |
| NCBI Full Name: | Integrator complex subunit 12 |
| NCBI Synonym Full Names: | integrator complex subunit 12 |
| NCBI Official Symbol: | INTS12 |
| NCBI Official Synonym Symbols: | INT12; PHF22; SBBI22 |
| NCBI Protein Information: | integrator complex subunit 12; PHD finger protein 22; hypothetical nuclear factor SBBI22 |
| UniProt Protein Name: | Integrator complex subunit 12 |
| UniProt Synonym Protein Names: | PHD finger protein 22 |
| Protein Family: | Integrator complex |
| UniProt Gene Name: | INTS12 |
| UniProt Entry Name: | INT12_HUMAN |