INTS11 Polyclonal Antibody
- SKU:
- CAB22031
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | INTS11 Polyclonal Antibody |
| Product Code: | CAB22031 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293F |
| Cellular Location: | blood microparticle, cytoplasm, cytosol, nucleoplasm, nucleus |
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 331-600 of human INTS11 (NP_060341.2). |
| Sequence: | GQSLQ IFRKW AGNEK NMVIM PGYCV QGTVG HKILS GQRKL EMEGR QVLEV KMQVE YMSFS AHADA KGIMQ LVGQA EPESV LLVHG EAKKM EFLKQ KIEQE LRVNC YMPAN GETVT LPTSP SIPVG ISLGL LKREM AQGLL PEAKK PRLLH GTLIM KDSNF RLVSS EQALK ELGLA EHQLR FTCRV HLHDT RKEQE TALRV YSHLK SVLKD HCVQH LPDGS VTVES VLLQA AAPSE DPGTK VLLVS WTYQD EELGS FLTSL LKKGL PQAPS |
| Synonyms: | RC68, INT11, RC-68, CPSF3L, CPSF73L |
| Calculated MW: | 68kDa |
| Observed MW: | 68kDa |
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