Description
| Product Name: | INTS11 Monoclonal Antibody |
| Product Code: | CAB22698 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58804 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:7000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293F, Mouse spleen, Rat testis |
| Cellular Location: | blood microparticle, cytoplasm, cytosol, nucleoplasm, nucleus |
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).
| Immunogen: | Recombinant protein of human INTS11. |
| Sequence: | Email for sequence |
| Synonyms: | RC68, INT11, RC-68, CPSF3L, CPSF73L |
| Calculated MW: | 68kDa |
| Observed MW: | 68kDa |