Integrin alpha 1 (ITGA1/CD49a) Monoclonal Antibody

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SKU:
CAB22707

Description

Product Name:Integrin alpha 1 (ITGA1/CD49a) Monoclonal Antibody
Product Code:CAB22707
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58198
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:10000-1:120000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:SH-SY5Y, HeLa
Cellular Location:Membrane, Single-pass type I membrane protein

This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 29-1141 of human Integrin alpha 1 (ITGA1/CD49a) (NP_852478.1).
Sequence:FNVDV KNSMT FSGPV EDMFG YTVQQ YENEE GKWVL IGSPL VGQPK NRTGD VYKCP VGRGE SLPCV KLDLP VNTSI PNVTE VKENM TFGST LVTNP NGGFL ACGPL YAYRC GHLHY TTGIC SDVSP TFQVV NSIAP VQECS TQLDI VIVLD GSNSI YPWDS VTAFL NDLLE RMDIG PKQTQ VGIVQ YGENV THEFN LNKYS STEEV LVAAK KIVQR GGRQT MTALG IDTAR KEAFT EARGA RRGVK KVMVI VTDGE SHDNH RLKKV IQDCE DENIQ RFSIA ILGSY NRGNL STEKF VEEIK SIASE PTEKH FFNVS DELAL VTIVK TLGER IFALE ATADQ SAASF EMEMS QTGFS AHYSQ DWVML GAVGA YDWNG TVVMQ KASQI IIPRN TTFNV ESTKK NEPLA SYLGY TVNSA TASSG DVLYI AGQPR YNHTG QVIIY RMEDG NIKIL QTLSG EQIGS YFGSI LTTTD IDKDS NTDIL LVGAP MYMGT EKEEQ GKVYV YALNQ TRFEY QMSLE PIKQT CCSSR QHNSC TTENK NEPCG ARFGT AIAAV KDLNL DGFND IVIGA PLEDD HGGAV YIYHG SGKTI RKEYA QRIPS GGDGK TLKFF GQSIH GEMDL NGDGL TDVTI GGLGG AALFW SRDVA VVKVT MNFEP NKVNI QKKNC HMEGK ETVCI NATVC FDVKL KSKED TIYEA DLQYR VTLDS LRQIS RSFFS GTQER KVQRN ITVRK SECTK HSFYM LDKHD FQDSV RITLD FNLTD PENGP VLDDS LPNSV HEYIP FAKDC GNKEK CISDL SLHVA TTEKD LLIVR SQNDK FNVSL TVKNT KDSAY NTRTI VHYSP NLVFS GIEAI QKDSC ESNHN ITCKV GYPFL RRGEM VTFKI LFQFN TSYLM ENVTI YLSAT SDSEE PPETL SDNVV NISIP VKYEV GLQFY SSASE YHISI AANET VPEVI NSTED IGNEI NIFYL IRKSG SFPMP ELKLS ISFPN MTSNG YPVLY PTGLS SSENA NCRPH IFEDP FSINS GKKMT TSTDH LKRGT ILDCN TCKFA TITCN LTSSD ISQVN VSLIL WKPTF IKSYF SSLNL TIRGE LRSEN ASLVL SSSNQ KRELA IQISK DGLPG RVP
Synonyms:VLA1, CD49a
Calculated MW:131kDa
Observed MW:200kDa
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Additional Information

Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
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