Description
Product Name: | Integrin-β1/CD29 Monoclonal Antibody |
Product Code: | CAB21234 |
Reactivity: | Human, Mouse, Rat |
Applications: | Immunofluorescence, Flow Cytometry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC52468 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | IF/ICC, FC, ELISA |
Key Applications: | Immunofluorescence, Flow Cytometry |
Recommended Dilution: | IF/ICC 1:50-1:200, FC 5 μl per 10, ^6 cells in 100, μl volume |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Cellular Location: | Cell junction, Cell membrane, Cell projection, Cleavage furrow, Melanosome, Recycling endosome, Single-pass type I membrane protein, invadopodium membrane, lamellipodium, ruffle membrane, ruffle, sarcolemma |
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-728 of human Integrin-β1/CD29 (NP_002202.2). |
Sequence: | MNLQP IFWIG LISSV CCVFA QTDEN RCLKA NAKSC GECIQ AGPNC GWCTN STFLQ EGMPT SARCD DLEAL KKKGC PPDDI ENPRG SKDIK KNKNV TNRSK GTAEK LKPED ITQIQ PQQLV LRLRS GEPQT FTLKF KRAED YPIDL YYLMD LSYSM KDDLE NVKSL GTDLM NEMRR ITSDF RIGFG SFVEK TVMPY ISTTP AKLRN PCTSE QNCTS PFSYK NVLSL TNKGE VFNEL VGKQR ISGNL DSPEG GFDAI MQVAV CGSLI GWRNV TRLLV FSTDA GFHFA GDGKL GGIVL PNDGQ CHLEN NMYTM SHYYD YPSIA HLVQK LSENN IQTIF AVTEE FQPVY KELKN LIPKS AVGTL SANSS NVIQL IIDAY NSLSS EVILE NGKLS EGVTI SYKSY CKNGV NGTGE NGRKC SNISI GDEVQ FEISI TSNKC PKKDS DSFKI RPLGF TEEVE VILQY ICECE CQSEG IPESP KCHEG NGTFE CGACR CNEGR VGRHC ECSTD EVNSE DMDAY CRKEN SSEIC SNNGE CVCGQ CVCRK RDNTN EIYSG KFCEC DNFNC DRSNG LICGG NGVCK CRVCE CNPNY TGSAC DCSLD TSTCE ASNGQ ICNGR GICEC GVCKC TDPKF QGQTC EMCQT CLGVC AEHKE CVQCR AFNKG EKKDT CTQEC SYFNI TKVES RDKLP QPVQP DPVSH CKEKD VDDCW FYFTY SVNGN NEVMV HVVEN PECPT GPD |
Synonyms: | CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA |
Calculated MW: | 88kDa |