INSC Antibody (PACO09967)
- SKU:
- PACO09967
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | INSC Antibody (PACO09967) |
| Antibody SKU: | PACO09967 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human INSC |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | inscuteable homolog (Drosophila); |
| UniProt Protein Function: | INSC: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium. 5 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 11p15.2 |
| UniProt Protein Details: | |
| NCBI Summary: | In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q1MX18 |
| NCBI GenInfo Identifier: | 116248172 |
| NCBI Gene ID: | 387755 |
| NCBI Accession: | Q1MX18.1 |
| UniProt Secondary Accession: | Q1MX18,Q1MX19, Q3C1V6, Q4AC95, Q4AC96, Q4AC97, Q4AC98 A0PJX5 |
| UniProt Related Accession: | Q1MX18 |
| Molecular Weight: | 57,188 Da |
| NCBI Full Name: | Protein inscuteable homolog |
| NCBI Synonym Full Names: | inscuteable homolog (Drosophila) |
| NCBI Official Symbol: | INSC |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | protein inscuteable homolog |
| UniProt Protein Name: | Protein inscuteable homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein inscuteable |
| UniProt Gene Name: | INSC |
| UniProt Entry Name: | INSC_HUMAN |
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