ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)
![ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58820/64002/assay-genie-box-4__65654.1706535227.jpg?c=1 "ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)")
- SKU:
- CPAB0600
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT39E5AT
- Applications:
- WB
- Applications:
- ELISA
![ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58820/64002/assay-genie-box-4__65654.1706535227.jpg?c=1&imbypass=on "ING2 Monoclonal Antibody [PAT39E5AT] (CPAB0600)")
Description
system_update_alt Datasheet
| Product Name: | ING2 Antibody |
| Product Sku: | CPAB0600 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human ING2 mAb, clone PAT39E5AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ING2 protein 1-28 amino acids purified from Ecoli. |
| Clone: | PAT39E5AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | ING2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | Inhibitor of Growth Family, Member 2 (ING2) belongs to the inhibitor of growth (ING) family. ING family members associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and serve in DNA repair and apoptosis. ING2 appears to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, most likely by enhancing acetylation of p53/TP53. ING2 is a component of an mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity is modulated by binding to phosphoinositides (PtdInsPs). |
| Synonyms: | Inhibitor Of Growth Family Member 2, ING1L, Inhibitor Of Growth 1-Like Protein, P33ING2, ING1Lp, P32, Inhibitor Of Growth Family Member 1-Like, Inhibitor Of Growth Protein 2, ING2. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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