IMMP2L Antibody (PACO45546)
- SKU:
- PACO45546
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | IMMP2L Antibody (PACO45546) |
| Antibody SKU: | PACO45546 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Mitochondrial inner membrane protease subunit 2 protein (1-100AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO45546 at dilution of 1:100. |
| Background: | Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. |
| Synonyms: | Mitochondrial inner membrane protease subunit 2 (EC 3.4.21.-) (IMP2-like protein), IMMP2L |
| UniProt Protein Function: | IMMP2L: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. Defects in IMMP2L may be a cause of Gilles de la Tourette syndrome (GTS). GTS is a neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Belongs to the peptidase S26 family. IMP2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.4.21.-; Mitochondrial; Membrane protein, integral; ProteaseChromosomal Location of Human Ortholog: 7q31Molecular Function: peptidase activity; serine-type endopeptidase activityBiological Process: mitochondrial protein processing; mitochondrial respiratory chain complex assembly; signal peptide processing |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011] |
| UniProt Code: | Q96T52 |
| NCBI GenInfo Identifier: | 74752143 |
| NCBI Gene ID: | 83943 |
| NCBI Accession: | Q96T52.1 |
| UniProt Secondary Accession: | Q96T52,Q75MF1, Q75MN9, Q75MP0, Q75MS5, Q75MS8, Q96HJ2 |
| UniProt Related Accession: | Q96T52 |
| Molecular Weight: | 12,259 Da |
| NCBI Full Name: | Mitochondrial inner membrane protease subunit 2 |
| NCBI Synonym Full Names: | inner mitochondrial membrane peptidase subunit 2 |
| NCBI Official Symbol: | IMMP2L |
| NCBI Official Synonym Symbols: | IMP2; IMP2-LIKE; IMMP2L-IT1 |
| NCBI Protein Information: | mitochondrial inner membrane protease subunit 2 |
| UniProt Protein Name: | Mitochondrial inner membrane protease subunit 2 |
| UniProt Synonym Protein Names: | IMP2-like protein |
| Protein Family: | |
| UniProt Gene Name: | IMMP2L |
| UniProt Entry Name: | IMP2L_HUMAN |
| Antibodies |
| IMMP2L Antibody (PACO09945) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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