ILT5/CD85a Monoclonal Antibody
- SKU:
- CAB24714
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- FC
Description
| Product Name: | ILT5/CD85a Monoclonal Antibody |
| Product Code: | CAB24714 |
| Reactivity: | Human |
| Applications: | Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64515 |
| Reactivity: | Human |
| Tested Applications: | FC, ELISA |
| Key Applications: | Flow Cytometry |
| Recommended Dilution: | FC 1:200-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-418 of human ILT5/CD85a (NP_006855.3). |
| Sequence: | GPFPK PTLWA EPGSV ISWGS PVTIW CQGSQ EAQEY RLHKE GSPEP LDRNN PLEPK NKARF SIPSM TEHHA GRYRC HYYSS AGWSE PSDPL EMVMT GAYSK PTLSA LPSPV VASGG NMTLR CGSQK GYHHF VLMKE GEHQL PRTLD SQQLH SRGFQ ALFPV GPVTP SHRWR FTCYY YYTNT PWVWS HPSDP LEILP SGVSR KPSLL TLQGP VLAPG QSLTL QCGSD VGYNR FVLYK EGERD FLQRP GQQPQ AGLSQ ANFTL GPVSP SNGGQ YRCYG AHNLS SEWSA PSDPL NILMA GQIYD TVSLS AQPGP TVASG ENVTL LCQSW WQFDT FLLTK EGAAH PPLRL RSMYG AHKYQ AEFPM SPVTS AHAGT YRCYG SYSSN PHLLS HPSEP LELVV |
| Synonyms: | LILRB3, CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIR-B, PIRB, leukocyte immunoglobulin like receptor B3 |
| Calculated MW: | 69kDa/71kDa |
| Observed MW: | Refer to figures |
Related Products
Human LILRB3/LIR3/ILT5/CD85a Recombinant Protein (RPES0488)
Mouse LILRB3/LIR3/ILT5/CD85a Recombinant Protein (RPES4670)
![HA Monoclonal Monoclonal Antibody [PHASHG] (CPAB0489)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/590x590/products/58711/63893/ha-monoclonal-monoclonal-antibody-phashg-cpab0489__29794__44162.1706535192.jpg?c=1 "HA Monoclonal Monoclonal Antibody [PHASHG] (CPAB0489)")
CD27 Monoclonal Antibody
