IL6 Polyclonal Antibody
- SKU:
- CAB24522
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IL6 Polyclonal Antibody |
| Product Code: | CAB24522 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Recombinant mouse IL6 Protein(100ng), Recombinant mouse IL6 Protein(10ng) |
This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-211 of mouse IL6 (NP_112445.1). |
| Sequence: | FPTSQ VRRGD FTEDT TPNRP VYTTS QVGGL ITHVL WEIVE MRKEL CNGNS DCMNN DDALA ENNLK LPEIQ RNDGC YQTGY NQEIC LLKIS SGLLE YHSYL EYMKN NLKDN KKDKA RVLQR DTETL IHIFN QEVKD LHKIV LPTPI SNALL TDKLE SQKEW LRTKT IQFIL KSLEE FLKVT LRSTR QT |
| Synonyms: | Il-6 |
| Calculated MW: | 24kDa |
| Observed MW: | 25-35kDa |
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