IL6 Monoclonal Antibody (CAB22222)
- SKU:
- CAB22222
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IL6 Monoclonal Antibody |
| Product Code: | CAB22222 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC5093-01 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HUVEC |
| Cellular Location: | Secreted |
| Customer Validation: | WB(Homo sapiens, Mus musculus ) |
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).
| Immunogen: | Recombinant protein of human IL6. |
| Sequence: | VPPGE DSKDV AAPHR QPLTS SERID KQIRY ILDGI SALRK ETCNK SNMCE SSKEA LAENN LNLPK MAEKD GCFQS GFNEE TCLVK IITGL LEFEV YLEYL QNRFE SSEEQ ARAVQ MSTKV LIQFL QKKAK NLDAI TTPDP TTNAS LLTKL QAQNQ WLQDM TTHLI LRSFK EFLQS SLRAL RQM |
| Synonyms: | CDF, HGF, HSF, BSF2, IL-6, BSF-2, IFNB2, IFN-beta-2 |
| Calculated MW: | 24kDa |
| Observed MW: | 24kDa |
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