IL4I1 Monoclonal Antibody
- SKU:
- CAB23151
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | IL4I1 Monoclonal Antibody |
| Product Code: | CAB23151 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54077 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:10000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Human plasma |
| Cellular Location: | Lysosome |
This gene encodes a secreted L-amino acid oxidase protein which primarily catabolizes L-phenylalanine and, to a lesser extent, L-arginine. The expression of this gene is induced by the cytokine interleukin 4 in B cells. This gene is also expressed in macrophages and dendritic cells. This protein may play a role immune system escape as it is expressed in tumor-associated macrophages and suppresses T-cell responses. This protein also contains domains thought to be involved in the binding of flavin adenine dinucleotide (FAD) cofactor. Multiple transcript variants encoding different isoforms have been found for this gene. Some transcripts of this gene share a promoter and exons of the 5' UTR with the overlapping NUP62 gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IL4I1. |
| Sequence: | MAPLA LHLLV LVPIL LSLVA SQDWK AERSQ DPFEK CMQDP DYEQL LKVVT WGLNR TLKPQ RVIVV GAGVA GLVAA KVLSD AGHKV TILEA DNRIG GRIFT |
| Synonyms: | LAO, FIG1, LAAO, hIL4I1 |
| Calculated MW: | 63kDa |
| Observed MW: | 70kDa |
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