Description
Product Name: | IL4 Monoclonal Antibody |
Product Code: | CAB24733 |
Reactivity: | Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC61989 |
Reactivity: | Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Recombinant Mouse IL-4 Protein, Mouse testis, Rat thymus |
Cellular Location: | External side of plasma membrane, Extracellular space |
Enables cytokine activity. Involved in several processes, including innate immune response in mucosa; negative regulation of white fat cell proliferation; and regulation of gene expression. Acts upstream of or within several processes, including T-helper cell differentiation; positive regulation of macromolecule metabolic process; and regulation of leukocyte activation. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including brain; colon; hemolymphoid system; liver; and placenta. Used to study Sjogren's syndrome; atopic dermatitis; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); hepatitis B; hepatitis C; and pancreatic cancer (multiple). Orthologous to human IL4 (interleukin 4).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-140 of mouse IL4 (NP_067258.1). |
Sequence: | HIHGC DKNHL REIIG ILNEV TGEGT PCTEM DVPNV LTATK NTTES ELVCR ASKVL RIFYL KHGKT PCLKK NSSVL MELQR LFRAF RCLDS SISCT MNESK STSLK DFLES LKSIM QMDYS |
Synonyms: | Il-4, BSF-1 |
Calculated MW: | 16kDa |
Observed MW: | 16kDa/18kDa |